The TSE Rotameter is a computer-controlled system designed to analyze rotational movement following unilateral 6-hydroxydopamine lesions in rodents (6-OHDA model). Lesioned animals tend to rotate toward their impaired hemisphere and this rotational behavior is increased by subsequent drug treatment. The animal is tested in a special rotameter test cage that facilitates rotational movement. Bowl-shaped arenas are standard – smaller cylindrical arenas are available as a space-saving alternative. The animal is connected to a rotation sensor via a jacket and a flexible tether – the low-torque construction ensures that the animal’s movement is not restricted. The rotation sensor detects clockwise and counterclockwise rotations with a resolution of 1/250 turn.
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